Assays / Trace Metals/ Iodine

It is outside the remit of this handbook to discuss the role of iodine in thyroid function and the rationale for measurements of triiodothyronine (T3), thyroxine (T4), thyroid stimulating hormone (TSH) etc. However, it is important to note that the use of iodine-containing antimicrobial wash solutions following surgery can lead to iodine toxicity manifested as hyperthyroidism. Measurements of total serum iodine can be of value in assessing iodine toxicity. Iodine deficiency was detected in a child who had a delayed rate of growth after introduction of a restrictive diet for purported food sensitivity.
The reference range for iodine in serum is 0.32-0.63 µmol/L

References:
Labib M, Gama R, Wright JW, Marks V, Robins D. Dietary maladvice as a cause of hypothyroidism and short stature. BMJ, 1989; 298: 232-3

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