The Metabolic Bone Disease Unit and associated laboratories have existed on the Royal Liverpool University Hospital site for over 30 years. Both clinical and academic aspects of the management and investigation of bone metabolism have been developed during the past 12 years under the direction of Professor Bill Fraser. An international reputation has been established in the development, evaluation and application of assays for calcitropic hormones (PTH, PTHrP, vitamin D) and bone/collagen metabolism (pyridinoline cross-links (PYR,DPD) telopeptides (CTX,NTX, 1CTP), pro-collagen molecules (P1CP, P1NP, PIIINP), osteocalcin and bone specific alkaline phosphatase). The majority of these assays are available with weekly turnaround and a national/international service is provided for PTHrP. Investigation protocols, consultation and advice are available for all aspects of bone and calcium metabolism as part of the SAS.

Director: Professor WD Fraser
Tel: +44 (0)151 706 4247/ 4257
Fax: +44 (0)151 706 5813