The Lipid laboratory at St. Thomas’ provides specialist assay support for the long-established clinics at Guy’s and St. Thomas’ Hospitals. The laboratory has been involved in clinical research for 40 years measuring lipid fractions by ultracentrifugation, apolipoproteins, enzyme and transfer factor activities as well as markers of inflammation. Landmark studies conducted by the laboratory include the St. Thomas’ atherosclerosis regression trial (STARS), the Whitehall, Oxford and EuroDiab studies and numerous investigations in lipoprotein turnover in a variety of diseases.

The director, Dr Anthony Wierzbicki is interested in the genetics of hyperlipidaemia, the relationship between dyslipidaemia and hypertension, diseases of peroxisome metabolism (Refsum disease) and how drugs affect lipids and apolipoproteins. Dr Martin Crook, the deputy director, has long-standing interests in lipids in diabetes and obesity, the role played by apolipoprotein H as a cardiovascular and coagulation risk factor and the use of sialic acid as a marker of inflammation.

Tel:+44 (0)20 7188 1256
Fax:+44 (0)20 7928 4226