London UCL Hospital Adrenal Steroid Genetics Laboratory

University College (London) Hospital

The SAS Centre in this hospital cluster was among the first in the SAS and has had a long standing interest in adrenal steroidogenesis since the early discovery of aldosterone by Simpson and Tate at the Middlesex Hospital. The laboratory has an international reputation for steroid analysis and has published extensively on the clinical applications of the technique particularly in adrenal problems presenting in children. Other areas of interest include disorders of sex differentiation and hypertension.

Dr Rumsby has studied the molecular genetics of adrenal steroid biosynthetic defects and the lab now offers genetic diagnosis of the following steroid biosynthetic defects: 11 beta-hydroxylase, aldosterone synthase, 17 alpha-hydroxylase, 5 alpha reductase and 17 beta-hydroxysteroid reductase deficiencies.

Director: Dr Gill Rumsby – Tel: +44 (0)20344 72955
Deputy Director: Ian Phillips – Tel: +44 (0)20 344 72961

Department of Clinical Biochemistry
UCL Hospitals
3rd floor
60 Whitfield Street

Fax: +44 (0)20 344 79584